Tag Archives: Evolution in Reverse

Succinate As the Dominant Player in Krebs Cycle Bioenergetics

Majid Ali, M.D.  Succinate Circa 2004 Table 1. The Frequency of Increased* Urinary Excretion of Metabolites of the Krebs Cycle in 236 Patients with Dysoxygenosis Citric acid Succinic acid Aconitic acid Fumaric acid 2-oxo-glutaric acid 196 40 26 1 0 * Increases beyond the laboratory range for the general population. Levels of acids measured in mmol/mol creatinine. Succinate Circa 2015

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Disease Is Evolution-in-Reverse

Majid Ali, M.D. To understand the beginning of diseases, we first need to understand the beginning of life. This is impossibly complex one way and very simple in an another. Simply stated, evolution is the long (and continuing journey) which allowed the development of modern human cells from the primordial “pre-cells” (spherules that lived in he toxic primordial soup). Pre-cells were

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More Coronary Plaques, Fewer-Coronary Deaths – Part A

Majid Ali, M.D. The More-Coronary-Plaques-Fewer-Heart Attacks Paradox More arterial plaques are associated with fewer deaths from heart attacks and strokes. No, you did not misread the sentence. I write precisely what I mean: people with less intense plaque formation have higher mortality from cardiovascular diseases. I anticipate harsh frowns from doctors on the title of this tutorial. The idea that

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