Category Archives: AA Oxidopathy

Smoking Damages Blood Cells

Majid Ali, M.D. Blood Cells Before and After Cigarette Smoking   Students are invited to use the photographs of blood smears presented below to prepare school science projects after discussing it with their teachers. Ali M, Ali O. AA Oxidopathy: the core pathogenetic mechanism of ischemic heart disease. J Integrative Medicine 1997;1:1-112. Smoking and AA Oxidopathy Figure 21 (top) before

Read more

Breaking Up Blood Platelet Aggregates With Vitamin C

  Majid Ali, M.D. Children are invited to use the text and photographs (such as those below) on this web site for preparing competition essays and school science projects. Blood Platelet Clump Due to Oxidative Stress. Dissociation of Platelet Aggregates by Vitamin C   Figure 15 (top) shows patterns of aggregation of platelets induced by oxidative stress of epinephrine, collagen,

Read more

AA Oxidopathy Part One

Majid Ali, M.D.   AA Oxidopathy: The Core Pathogenetic Mechanism of Ischemic Heart Disease PART I Majid Ali, M.D., Omar Ali, M.D. Ali M, Ali O. AA Oxidopathy: the core pathogenetic mechanism of ischemic heart disease. J Integrative Medicine 1997;1:1-112. From the Departments of Medicine, Capital University of Integrative Medicine, Washington, D.C., and Institute of Preventive Medicine, New York (MA

Read more

AA OXIDOPATHY – PART 2 – Morphology

Majid Ali, M.D.     MORPHOLOGIC PATTERNS OF AA OXIDOPATHY Below we describe our high-resolution, phase-contrast morphologic observations that comprise AA oxidopathy and oxidative coagulopathy. The degree and extent of oxidative changes, of course, varies over a broad range depending on the number and the nature of oxidative stressors. During the early months of our work with AA oxidopathy, we

Read more

AA OXIDOPATHY – PART 3

Majid Ali, M.D. Coronary Artery Heart Disease Begins With AA Oxidopathy      AA OXIDOPATHY HYPOTHESIS IS CONSISTENT WITH ALL KNOWN MOLECULAR DYNAMICS OF IHD     Molecular dynamics that preserve the clotting-unclotting equilibrium (CUE) of life are marvels of biology. An elaborate system of coagulative proteins, fibrinolytic enzymes and inhibitors of fibrinolysis exists in the circulating blood that prevents clotting-unclotting

Read more

AA Oxidopathy References

  Majid Ali, M.D. SUMMARY Redox regulation in the circulating blood is a dynamic, elaborately integrated complex of diverse energetic-molecular events that involve all plasma and cellular oxidant-antioxidant systems. Changes of redox dysregulation in circulating blood comprise cell erythrocyte membrane damage and cell lysis, zones of plasma congealing, activation of polymorphonuclear leukocytes and monocytes, transformation of monocytes into macrophages, and

Read more