Majid Ali, M.D. Insulin – The Life Span Hormone Series of Free Oxygen Course Series Insulin – The Premium Life Span Hormone Human life span is put in jeopardy by disruptions of molecular biology of oxygen and insulin homeostasis; life expectancy of an individual is shortened by diminished signaling of the former1-8 as well as by excessive signaling of
Read moreOxygen homeostasis determines the state of health. Disruption of oxygen homeostasis lead to absence of health and disease. Impeded Oxygen Signaling I coined the term oxygen signaling for all cues and commands given by oxygen, or its absence, to cells and tissues for energetic, buoilding or dismantling reactions. Impeded oxygen signaling is the fundamental energetic-molecular derangement in all
Read moreMajid Ali, M.D. Oxygen for Health and Healing UNDERSTANDING OXYGEN TO UNDERSTAND HEALTH/DIS-EASE/DISEASE CONTINUUM — AND CONSCIOUSNESS Oxygen is the organizing influence of human biology and governs the aging process. It is the primary “energy-nutrient” molecule of human biology. It is an exquisitely discriminating regulator of all developmental, metabolic, and detoxification mechanisms. It is the weapon of transcending importance in
Read moreMajid Ali, M.D. I coined the term oxygen signaling to refer to all biological roles of oxygen in which the presence or absence of oxygen triggers, perpetuates, modifies, suppresses, or terminates biologic reactions with or without direct involvement of energy generation, utilization, conservation, or storage. Oxygen Is the Organizing Principle of Human Biology and Governs the Aging Process In started
Read moreMajid Ali, M.D. The Pyramid of a Trio of Trios of Human Ecosystems for Establishing Clinical Priorities for Integrative Treatment of Chronic Diseases. The Pyramid of Ecosystems Oxygen’s Three-Legged Throne Acid-Alkali Balance Oxidant-Antioxidant Regulation Clotting-Unclotting Equilibrium
Read moreMajid Ali, M.D. In my book “Dr. Ali’s Plan for Reversing Diabetes” (2011), I introduced the following terms: Ali’s Diabetes Reversal Plan© for a plan for restoring insulin homeostasis (overall balance) and Insulin-based Diabetes Reversal Plan©. Insulin Tox © as an abbreviation for insulin toxicity©. Insulin Detox© as an abbreviation for a non-drug program of reversing insulin toxicity© focusing
Read moreMajid Ali, M.D. Blood Cells Before and After Cigarette Smoking Students are invited to use the photographs of blood smears presented below to prepare school science projects after discussing it with their teachers. Ali M, Ali O. AA Oxidopathy: the core pathogenetic mechanism of ischemic heart disease. J Integrative Medicine 1997;1:1-112. Smoking and AA Oxidopathy Figure 21 (top) before
Read moreMajid Ali, M.D. Children are invited to use the text and photographs (such as those below) on this web site for preparing competition essays and school science projects. Blood Platelet Clump Due to Oxidative Stress. Dissociation of Platelet Aggregates by Vitamin C Figure 15 (top) shows patterns of aggregation of platelets induced by oxidative stress of epinephrine, collagen,
Read moreMajid Ali, M.D. AA Oxidopathy: The Core Pathogenetic Mechanism of Ischemic Heart Disease PART I Majid Ali, M.D., Omar Ali, M.D. Ali M, Ali O. AA Oxidopathy: the core pathogenetic mechanism of ischemic heart disease. J Integrative Medicine 1997;1:1-112. From the Departments of Medicine, Capital University of Integrative Medicine, Washington, D.C., and Institute of Preventive Medicine, New York (MA
Read moreMajid Ali, M.D. MORPHOLOGIC PATTERNS OF AA OXIDOPATHY Below we describe our high-resolution, phase-contrast morphologic observations that comprise AA oxidopathy and oxidative coagulopathy. The degree and extent of oxidative changes, of course, varies over a broad range depending on the number and the nature of oxidative stressors. During the early months of our work with AA oxidopathy, we
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