The Lisinopril-Laryngitis Connection

Majid Ali, M.D.

The ACE Inhibitors and Their Inflammatory Reactions


Lisinopril is a hypertension drug belonging to a class of drugs called ACE inhibitors. estimates An estimated 20% of individuals taking any of ACE drugs develop a dry cough, the cause of which regrettably goes unrecognized for months or longer. Other undesirable inflammatory responses triggered by lisinopril include symptoms similar to those seen in rhinitis (nasal congestion and inflammation), sinusitis, laryngitis, and GERD-like symptoms, The treatment in such cases is simple: stop the drug.


ACDE stands for Angiotensin-Converting Enzyme and ACE inhibitor drugs work by blocking the effects of this enzyme. Other names of this enzyme are kininase II and bradykinin dehydrogenase.

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