Testosterone Is Not Bad for Prostate Cancer

Majid Ali, M.D.

Testosterone has been needlessly demonized for causing or feeding prostate cancer. There is no scientific evidence for this view. Low testosterone activity in the body in men impairs health in many ways and weakens immunity. So, the prevailing practice of withholding testosterone replacement therapy from individuals with high PSA values or prostate cancer without specific reason needs to be re-evaluated.


Many elderly men have memory and concentration problems which often respond well to testosterone therapy. Some of these men have elevated blood levels of PSA (prostate-specific antigen), a marker of prostate cancer, withholding testosterone from such individuals without specific reasons is another important concern in this context.


Consider the following text in the conclusion section of a large meta-analysis article published in 2014 in the Journal Prostate Cancer Prostate Diseases (2014;17:132-143.)

“This meta-analysis shows that regardless of the administration method, TRT is the short-term safety and does not promote prostate cancer development or progression but long-term data are warranted with justifiable end points.”

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