Testosterone Is a Health Hormone

 Majid Ali, M.D.

Testosterone is not merely a hormone for male sexual function. Thinking of the hormone in this light is the root of most misconceptions about the roles of this hormone in preserving memory and other mental functions, muscle strength, heart health, bone resilience, and other functions in both men and women.

It is essential to recognize that all so-called sex hormones (testosterone, estrogens, and progesterone) are “health hormones” and are responsible for the health of all hormones. We really do not need any studies to show that these hormones are essential for memory or the health of the heart and bones.

Testosterone belongs to the class of androgen steroid hormone and plays the primary role in the development of male reproductive tissues, such as the testis and prostate. It also promotes the development of secondary sexual characteristics, such as larger muscle and bone masses and the growth of body-hair. It is the principal sex hormone in males but is also crucial for female sexuality. Testosterone is a powerfully anabolic steroid.

An adult human male produces about ten times more testosterone than an adult human female. However, females are more sensitive to the hormone.

Testosterone and Cardiovascular Health

Testosterone plays important roles maintaining cardiovascular health. For example, maintaining normal testosterone levels in elderly men improve many parameters which are thought to reduce cardiovascular disease risk, such as improved insulin functions, control of insulin toxicity, better glycemic control, increased lean body mass, and decreased abdominal (visceral) fat mass. The mechanisms of these actions involve protein synthesis and growth of those tissues with androgen receptors.

In physiologic doses, testosterone has anti-inflammatory effects and improves the fluid characteristics of the circulating blood. For example, it regulates the population of a type of receptor on platelet-making cells in the bone marrow called thromboxane A2 receptors.

In mammals, testosterone is primarily produced in the testes of males and the ovaries of females. Smaller amounts are secreted by the adrenal glands.

Molecular Structure of Testosterone

Dr. Ali’s Course on Testosterone 

Dr. Ali’s Course on Testosterone

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