Insulin-Toxic Inflammatory Disorders

The Insulin-Inflammation Links

Majid Ali, M.D.

Insulin in excess is strongly pro-inflammatory hormone. Indeed, pathologic inflammation induced by hyperinsulinemia plays central roles in weight gain, neuropathy, nephropathy, retinopathy, and other pathologic entities associated with pre-diabetes, gestational diabetes, Type 2 diabetes, and insulin toxicity caused by improper use of insulin (for example by insulin injections taken after poor food choices). In this tutorial, I offer some interesting historical facts about pro-inflammatory of excess insulin. I follow this with an illustratiice case study.

In 1876, W. Ebstein, a German physician, reported that simple aspirin relieved many of the symptoms of diabetes in some patients. In 1901, R.T. Williamson, a British physician, validated Ebstein’s observation. His paper published in the British Medical Journal included the following: “sodium salicylate had a definite influence in greatly diminishing the sugar excretion.” These early papers went unnoticed. In 1957, another paper in the British Medical Journal reported on the case of an insulin-dependent individual whose arthritis was treated with high-dose aspirin regimen. Unexpectedly, he did not require any insulin injections during the treatment.

An Illuminating case Study

Recently, I saw a 57-year-old male nurse with a 21-year history of diabetes, hypertension, coronary artery stent, early kidney failure, and fatigue. When I told him that I wanted to do a four-hour insulin profile test. He looked puzzled and then said:

“My diabetologist never brought that subject up. He keeps increasing the dose of insulin every time my blood sugar level rises. Why do you think doing an insulin profile test will help?”

“I want to know how much insulin you might be wasting.” I replied.

“Why would I be wasting insulin?”

“Insulin wasting occurs when insulin receptor is blocked, blood sugar levels continue to rise, and the pancreas keeps producing more and more insulin.”

“How is insulin receptor blocked?”

“By toxicities of foods, environment, and thought.”

“What is insulin waste?”

“Insulin wasting is a state in which the pancreas keeps pouring insulin into the blood but the insulin simply cannot turn the crank-shaft of insulin receptors in the cell membranes—the gummed cell membranes block the insulin action, so to speak.” I explained.

He stared at me for several moments, then spoke, “You hit the nail on the head. When I was hospitalized for congestive heart failure and an increasing degree of kidney failure, they were able to control my glucose with one-fifth the insulin dose which I was taking before ending up in the hospital.”

“That was so because in the hospital your lungs were loaded with fluids, your kidneys were shutting down, your heart was overburdened, your tissues were water-logged and brimming with stagnant acids and, as a consequence of all those problems, you were struggling with free radical storms. You’re also insulin-toxic. They gave you oxygen, cleared the water from your lungs, supported your kidney function, and drained the stagnant acids out of your water-logged tissues. With those therapies, they controlled the free radical storms in your body. As a result of all that, they improved oxygen utilization in your cells and saved you from insulin toxicity,” I explained.

“Makes perfect sense, doesn’t it,” he beamed.

“Yes, It does.”

“What do we do now?”

“Now, we address all relevant issues of optimal food choices, physical exercise, and the bowel, blood, and liver toxicity. We will attempt to clean up your cell membranes so that your insulin can efficiently turn the crankshaft of insulin receptors in those membranes. You will then need much less insulin and will be able to avoid insulin toxicity.” I outlined our integrative program for him.

Insulin Toxicity Course

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