Five-Dimensional Hormone-Thinking for Testosterone, Estrogens, and Progesterone

Majid Ali, M.D.   

I present the subject of sex (gonadal) hormone health by raising three questions:
☞ What did my professors and medical textbooks teach me about hormonal balance? ☞ What did evolutionary intelligent design teach me about hormonal homeostasis? ☞ What did my patients—the truest of all my teachers teach me about hormonal healing?
What Did My Professors Teach?
In 1958, my medical professors did one-hormone-one-symptom thinking. They taught us to do the same. They lectured about estrogens, progesterone, and testosterone as single entities, and seldom, if ever, talked about how these pieces fitted into the ever-changing kaleidoscope of the health/dis-ease/disease continuum. Yes, they did teach that too much testosterone is bad for women and execess estrogens are not good for men. Back then, not much was known about the hormone receptor dysfunction—most doctors still do not think of the receptors—so one cannot think unkindly of my professors then. What can one say of medical professors who still do not think of hormone receptors? Or the doctors why never attempt to restore hormone receptor health?
What Did Evolutionary Intelligent Design Teach?
Human beings are energetic-molecular kaleidoscopes in which all pieces—hormones, hormone recptors embedded in cell membranes, and DNA response elements in the present context—sense and respond to the changing needs of all other pieces. When one thing in this kaleidoscope changes in one way, everything changes in some way. I present this holistic, ecologic, and integrative view of hormonal health and healing at length in my three-DVD set entitled “Hormone Triology” available at:
The discussion of the roles of genes and environments in hormonal health are frivolous, since gene-environment interactions are dynamic and ever-changing. Otherwise we humans would have been microbes—at some level, it seems to me, we still are. 
What Did My patients, the Truest of My Teachers, Teach?
My patients dared me to reach beyond the one-hormone-one-symptom one-dimensional thinking.  They compelled me to think five-dimensionally about hormonal health and healing . Specifically, they raise the following five questions:
* What do hormones do? * What do hormone receptors do? * What does the liver do? * What does the bowel do? * What does spiritual equilibrium do for gonadal hormonal equilibrium?
These questions force vus to think holistically and examine the essential connectivity of various ecosystems in the body.
One gift of understanding given to me by patients with menstrual and hormonal disorders is: hormone receptor restoration (RRT) is far more important for enduring good clinical results than the prevailing hormone replacement therapy (HRT). In 1998, as the editor of Journal of Integrative Medicine , I devoted a full issue of the journal to the subject of RRT. I introduced the term RRT (for hormone receptor restoration) to sharply contrast it with HRT.

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