Insulin Toxicity Case Two – Severe Insulin Toxicity In Polycystic Ovarian Syndrome

Insulin Toxicity Case Two

Severe Insulin Toxicity In Polycystic Ovarian Syndrome

Majid Ali, M.D.

Polycystic Ovarian Syndrome (PCOS) is a metabolic disorder with insulin toxicity and testosterone toxicity as the two primary derangement. In many cases, ovarian cysts appear late after other serious consequences of these two toxicities have proceeded to their full-blown clinical manifestations. In my personal series of PCOS cases, testosterone levels rose after sustained elevations of blood insulin levels. The case presented below is an excellent example of this.


Insulin and Glucose Profile of 17- yr-old 5’3″ Girl Weighing 204 lbs. Who Presented With Rapid Weight Gain, Facial Hair, Pigmentation Changes, IBS, Headache, Pre-hypertension, Mood Swings, and Fatty Change of the Liver

4.19.,2014

Fasting

1/2 Hr

1 Hr

2 Hr

3 Hr

Insulin

21.9

58.5

57.8

116.3

101.9

Glucose

88

127

153

152

119

Blood testosterone level, 27 ng/mL.

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