A1c Blood Test for Diabetes

              A1c Blood Test for Diabetes

Majid Ali, M.D.

Here are the seven core messages of this article about the A1c blood test:

* It is excellent for screening for diabetes.

* It is not reliable for detecting insulin toxicity that precedes the diagnosis of Type 2 diabetes by several years.

* It is excellent for monitoring the efficacy of glucose control in diabetes.

* It is not a good test if the goal is to get rid of diabetes—de-diabetize yourself, in my language.

* It can save us from making the serious mistake of relying on the fasting blood sugar test.

* It is not acceptable for determining if you are not insulin-toxic anymore after an insulin-conserving (insulin-reducing) program.

* The clinical value of the test can be significantly increased when the test results are trended —changes in the values are examined over a period of time.

I present the scientific basis of the above statement in my book entitled “Oxygen, Darwin’s Drones, and Diabetes. Volume 1—Dr. Ali’s Plan for Reversing Diabetes” (2011). It is available as an instant download at www.aliacademy.org. Th e print copies can be ordered from this website as well.

What Is A1c?

A1c is a protein made sticky by having glucose stuck to it. This protein is contained in red blood cells. It is called hemoglobin and carries oxygen. Proteins attached to sugars are called glycoproteins, which that makes A1c a glycoprotein. A1c is known by several names, including glycated hemoglobin, hemoglobin A1c, HbA1c, A1C, and Hb1c.

The American Diabetes Association (ADA) advises its followers—I clearly do not have that distinction—to diagnose diabetes mellitus when the A1c test value is 6.5% or higher of total hemoglobin (48 mmol/l or more). I explain my reasons for strongly disagreeing with the ADA dogma in my book on reversing diabetes book.

A Brief Historical Note

A1c was first recognized as a specific form of hemoglobin by Drs. Huisman and Meyering in the year (1958) when I joined King Edward Medical College, Lahore, Pakistan. Ten years later, Drs. Bookchin and Gallop characterized it as a glycoprotein. The raised vales of A1c in diabetes were described by Dr. Samuel Rahbar and his colleagues in 1969. In 1976, the clinical use of A1c for diabetes was proposed by Drs. Cerami, Koenig and their coworkers. This, as I show in some case studies, is not optimal.

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